Deep brain stimulation

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Risks

By Mayo Clinic staff

Although deep brain stimulation is generally safe, any type of surgery has the risk of complications. Also, the brain stimulation itself may cause side effects.

Surgery risks
Deep brain stimulation involves boring small holes in the skull to implant the electrodes, and surgery to implant the device that contains the batteries under the skin in the chest. Complications of surgery may include:

  • Bleeding in the brain (hemorrhage)
  • Stroke
  • Infection
  • Breathing problems
  • Nausea
  • Heart problems
  • Incision scarring

With deep brain stimulation, surgery isn't a one-time procedure. The batteries that are implanted in the chest have a limited life span, and when they run out, your symptoms may quickly return. Replacing the batteries requires another surgery. It's also possible for a wire connecting the batteries to an electrode to break or for other malfunctions to occur.

Possible side effects after surgery
Side effects associated with deep brain stimulation may include:

  • Seizure
  • Infection
  • Headache
  • Insomnia
  • Memory problems
  • Temporary pain and swelling at the implantation site

A few weeks after the surgery, the device will be turned on and the process of finding the best settings for you begins. This process may take several months. Some settings may cause side effects, but these often improve with further adjustments of your device.

Possible side effects of stimulation

  • Numbness or tingling sensations
  • Muscle tightness of the face or arm
  • Speech problems
  • Balance problems
  • Lightheadedness
  • Unwanted mood changes, such as mania and depression
References
  1. Deep brain stimulation for Parkinson's disease. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/deep_brain_stimulation/deep_brain_stimulation.htm. Accessed Oct. 13, 2012.
  2. Kluger BM, et al. Surgical treatment of movement disorders. Neurology Clinics. 2009;27:633.
  3. Brunicardi FC, ed., et al. Schwartz's Principles of Surgery. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=50. Accessed Oct. 11, 2012.
  4. Katz M, et al. Referring patients for deep brain stimulation. Archives of Neurology. 2011;68:1027.
  5. Ward HE, et al. Update on deep brain stimulation for neuropsychiatric disorders. Neurobiology of Disease. 2010;38:346.
  6. Magis D, et al. Neurostimulation therapies for primary headache disorders: present and future. Current Opinion in Neurology. 2012;25:269.
  7. Bronstein JM, et al. Deep brain stimulation for Parkinson disease. Archives of Neurology. 2011;68:165.
  8. Sankar T, et al. Novel applications of deep brain stimulation. Surgical Neurology International. 2012;3(suppl 1):S26.
  9. Deep brain stimulation. American Association of Neurological Surgeons. http://www.aans.org/Patient%20Information/Conditions%20and%20Treatments/Deep%20Brain%20Stimulation.aspx. Accessed Oct. 13, 2012.
  10. Klassen BT (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 13, 2012.
MY00184 Jan. 10, 2013

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