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Definition
By Mayo Clinic staff
Deep vein thrombosis (DVT) is a condition in which a blood clot (thrombus) forms in one or more of the deep veins in your body, usually in your legs. Deep vein thrombosis can cause leg pain, but often occurs without any symptoms.
Deep vein thrombosis can develop if you're sitting still for a long time, such as when traveling by plane or car, or if you have certain medical conditions that affect how your blood clots.
Deep vein thrombosis is a serious condition because a blood clot that has formed in your vein can break loose, travel through your bloodstream and lodge in your lungs, blocking blood flow (pulmonary embolism).
References
- Deep vein thrombosis. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/Dvt/DVT_All.html. Accessed May 29, 2011.
- Goldhaber SZ. Deep venous thrombosis and pulmonary embolism. In: Fauci AS, et al. Harrison's Online. 17th ed. New York, N.Y.: The McGraw-Hill Companies. 2008. http://www.accessmedicine.com/content.aspx?aID=2880540&searchStr=deep+vein+thrombosis#2880540. Accessed May 28, 2011.
- Deep vein thrombosis (DVT). Society for Vascular Surgery. https://www.vascularweb.org/vascularhealth/Pages/deep-vein-thrombosis-(-dvt-)-.aspx?PF=1. Accessed May 28, 2011.
- Focus on blood clots. Vascular Disease Foundation. http://www.vdf.org/pdfs/VDF_FocusOnBloodClots.pdf. Accessed May 29, 2011.
- O'Connor MB, et al. Inflammatory bowel disease, such as ulcerative colitis, is a risk factor for recurrent thromboembolic events: A case report. Cases Journal. 2009;2:173.
- Being tall, obese may significantly increase risk of blood clots in deep veins. American Heart Association. http://www.newsroom.heart.org/index.php?s=43&item=1321. Accessed May 29, 2011.
- Alguire PC, et al. Post-thrombotic (postphlebitic) syndrome. http://www.uptodate.com/home/index.html. Accessed May 27, 2011.
- Lip GY, et al. Treatment of lower extremity deep vein thrombosis. http://www.uptodate.com/home/index.html. Accessed May 27, 2011.
- FDA expands use of Xarelto to treat, reduce recurrence of blood clots. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm326654.htm?source=govdelivery. Accessed Jan. 2, 2013.
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