Complications
By Mayo Clinic staffThe primary complication to be concerned with in deep vein thrombosis is a pulmonary embolism.
Pulmonary embolism
A pulmonary embolism occurs when a blood vessel in your lung becomes blocked by a blood clot (thrombus) that travels to your lungs from another part of your body, usually your leg.
A pulmonary embolism can be fatal. So, it's important to be on the lookout for signs and symptoms of a pulmonary embolism and seek medical attention if they occur. Signs and symptoms of a pulmonary embolism include:
- Unexplained sudden onset of shortness of breath
- Chest pain or discomfort that worsens when you take a deep breath or when you cough
- Feeling lightheaded or dizzy, or fainting
- Rapid pulse
- Sweating
- Coughing up blood
- A sense of anxiety or nervousness
Postphlebitic syndrome
A common complication that can occur after deep vein thrombosis is a condition known as postphlebitic syndrome, also called postthrombotic syndrome. This syndrome is used to describe a collection of signs and symptoms, including:
- Swelling of your legs (edema)
- Leg pain
- Skin discoloration
This syndrome is caused by damage to your veins from the blood clot. This damage reduces blood flow in the affected areas. The symptoms of postphlebitic syndrome may not occur until a few years after the DVT. Treatment options include medications, such as aspirin or diuretics, as well as the use of compression stockings.
- Deep vein thrombosis. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/Dvt/DVT_All.html. Accessed May 29, 2011.
- Goldhaber SZ. Deep venous thrombosis and pulmonary embolism. In: Fauci AS, et al. Harrison's Online. 17th ed. New York, N.Y.: The McGraw-Hill Companies. 2008. http://www.accessmedicine.com/content.aspx?aID=2880540&searchStr=deep+vein+thrombosis#2880540. Accessed May 28, 2011.
- Deep vein thrombosis (DVT). Society for Vascular Surgery. https://www.vascularweb.org/vascularhealth/Pages/deep-vein-thrombosis-(-dvt-)-.aspx?PF=1. Accessed May 28, 2011.
- Focus on blood clots. Vascular Disease Foundation. http://www.vdf.org/pdfs/VDF_FocusOnBloodClots.pdf. Accessed May 29, 2011.
- O'Connor MB, et al. Inflammatory bowel disease, such as ulcerative colitis, is a risk factor for recurrent thromboembolic events: A case report. Cases Journal. 2009;2:173.
- Being tall, obese may significantly increase risk of blood clots in deep veins. American Heart Association. http://www.newsroom.heart.org/index.php?s=43&item=1321. Accessed May 29, 2011.
- Alguire PC, et al. Post-thrombotic (postphlebitic) syndrome. http://www.uptodate.com/home/index.html. Accessed May 27, 2011.
- Lip GY, et al. Treatment of lower extremity deep vein thrombosis. http://www.uptodate.com/home/index.html. Accessed May 27, 2011.
- FDA expands use of Xarelto to treat, reduce recurrence of blood clots. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm326654.htm?source=govdelivery. Accessed Jan. 2, 2013.


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