Causes
Feeling of depersonalization may:
- Begin with no apparent trigger
- Start after a life-threatening event, such as an accident or assault
- Be triggered by fear of having another depersonalization experience
With depersonalization disorder, feelings of depersonalization aren't directly caused by drugs, alcohol or a medical condition. However, depersonalization may be triggered by stress or trauma, and it often occurs along with other mental health conditions such as anxiety, depression or schizophrenia. In some cases, it starts suddenly without an apparent cause.
While the exact cause of depersonalization disorder isn't well understood, it appears to be linked to an imbalance of certain brain chemicals (neurotransmitters).
- Depersonalization disorder. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed May 2, 2011.
- Simeon D. Depersonalization disorder: A contemporary overview. CNS Drugs. 2004;18:343.
- Hunter ECM, et al. The epidemiology of depersonalization and derealisation. Social Psychiatry and Psychiatric Epidemiology. 2004;39:9.
- Kihlstrom J, et al. Dissociative disorders. Annual Review of Clinical Psychology. 2005;1:227.


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