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Complications

By Mayo Clinic staff

Depression is a serious illness that can take a terrible toll on individuals and families. Untreated depression can result in emotional, behavioral and health problems that affect every area of your life. Complications associated with depression can include:

  • Alcohol abuse
  • Substance abuse
  • Anxiety
  • Heart disease and other medical conditions
  • Work or school problems
  • Family conflicts
  • Relationship difficulties
  • Social isolation
  • Suicide
References
  1. Depressive disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed Jan. 12, 2009.
  2. Depression. National Institute of Mental Health. http://www.nimh.nih.gov/health/publications/depression/index.shtml. Accessed Jan. 12, 2010.
  3. Loosen PT, et al. Mood disorders. In: Ebert MH, et al. Current Diagnosis and Treatment: Psychiatry. 2nd ed. New York, N.Y.: McGraw Hill; 2008. http://www.accessmedicine.com/content.aspx?aid=3285019. Accessed Jan. 12, 2010.
  4. Espinoza RT, et al. Diagnosis and management of late-life depression. http://www.uptodate.com/home/index.html. Accessed Jan. 12, 2010.
  5. Lyness JM. Depression: Epidemiology and pathogenesis. http://www.uptodate.com/home/index.html. Accessed Jan. 12, 2010.
  6. Hall-Flavin, DK (expert opinion). Mayo Clinic, Rochester, Minn. January 19, 2009.
  7. Katon W, et al. Initial treatment of depression in adults. http://www.uptodate.com/home/index.html. Accessed Jan. 12, 2010.
  8. Martinez M, et al. Psychopharmacology. In: Hales RE. Textbook of Psychiatry. Arlington, Va.: American Psychiatric Publishing; 2008. http://www.psychiatryonline.com/content.aspx?aID=320111. Accessed Jan. 12, 2009.
  9. van der Watt G, et al. Complementary and alternative medicine in the treatment of anxiety and depression. Current Opinion in Psychiatry. 2008;2:37.
  10. Mischoulon D. Update and critique of natural remedies as antidepressant treatments. Obstetrics & Gynecology Clinics of North America. 2009;36:789.
  11. Wahner-Roedler D. Treating 20 common conditions. In: Bauer B. Mayo Clinic Book of Alternative Medicine. New York, N.Y.: Time Inc.; 2007:174.
DS00175 Feb. 11, 2010

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