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Definition
By Mayo Clinic staffDermatomyositis (dur-muh-to-mi-uh-SI-tis) is an uncommon inflammatory disease marked by muscle weakness and a distinctive skin rash.
Dermatomyositis may occur at any age, but it mostly affects adults in their late 40s to early 60s, or children between 5 and 15 years of age. Dermatomyositis affects more women than men. The signs and symptoms of dermatomyositis usually develop gradually, over weeks or months.
Periods of remission, when symptoms of dermatomyositis improve spontaneously, may occur. Treatment can clear the skin rash and help you regain muscle strength and function.
- NINDS dermatomyositis information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/dermatomyositis/dermatomyositis.htm. Accessed May 6, 2009.
- Baer A. Advances in the therapy of idiopathic inflammatory myopathies. Current Opinion in Rheumatology. 2006;18:236.
- Dalakas MC. Inflammatory disorders of muscle: Progress in polymyositis, dermatomyositis and inclusion body myositis. Current Opinion in Neurology. 2004;17:561.
- Miller ML. Clinical manifestations and diagnosis of adult dermatomyositis and polymyositis. http://www.uptodate.com/home/index.html. Accessed May 8, 2009.
- Greenberg SA, et al. Uncertainties in the pathogenesis of adult dermatomyositis. Current Opinion in Neurology. 2004;17:359.
- Santmyire-Rosenberger B, et al. Skin involvement in dermatomyositis. Current Opinion in Rheumatology. 2003;15:714.
- Amato AA, et al. Treatment of idiopathic inflammatory myopathies. Current Opinion in Neurology. 2003;16:569.
- Oddis CV. Current approach to the treatment of polymyositis and dermatomyositis. Current Opinion in Rheumatology. 2000;12:492.
- Walker UA. Imaging tools for the clinical assessment of idiopathic inflammatory myositis. Current Opinion in Rheumatology. 2008;20:656.
- Miller ML, et al. Initial treatment of dermatomyositis and polymyositis in adults. http://www.uptodate.com/home/index.html. Accessed May 8, 2009.
- Miller ML, et al. Treatment of recurrent and resistant polymyositis and dermatomyositis. http://www.uptodate.com/home/index.html. Accessed June 15, 2009.
