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continued:

Diabetes and Alzheimer's linked

Reducing your risk of Alzheimer's

Based on today's knowledge, working with your health care team to prevent diabetes or manage your diabetes effectively is your best strategy to avoid complications — including those that may affect your brain.

Preventing diabetes or managing it successfully will also help you avoid other complications, including heart disease and damage to your eyes, kidneys and nerves in your feet.

Steps you can take to prevent or manage diabetes include:

  • Follow your health care team's recommendations about the best plan for monitoring your blood glucose, cholesterol level and blood pressure.
  • Eat healthy foods, including fruits and vegetables, lean meats, whole grains, and low-fat milk and cheese.
  • Exercise at least 30 minutes most days of the week.
  • If your doctor prescribes medication, take it on schedule.

Small steps can make a big difference. In a large study funded by the National Institute of Diabetes and Digestive and Kidney Diseases, participants with blood sugar levels slightly above normal (prediabetes) cut their risk of developing type 2 diabetes in half by losing as little as 5 to 7 percent of their body weight and exercising for 30 minutes five days a week. That weight loss translates to 10 to 14 pounds (4.5 to 6.4 kilograms) for a 200-pound (90.7-kilogram) person.

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References
  1. National diabetes statistics 2007. National Institute of Diabetes and Digestive and Kidney Diseases. http://diabetes.niddk.nih.gov/dm/pubs/statistics/index.htm. Accessed July 14, 2010.
  2. Strachan MWJ, et al. The relationship between type 2 diabetes and dementia. British Medical Bulletin. 2008;88:131.
  3. Feng-Ping L, et al. Diabetes and the risk of multisystem aging phenotypes: A systematic review and meta-analysis. PLoS One. 2009:4:e4144. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0004144. Accessed July 14, 2010.
  4. Shadlen MF, et al. Risk factors for dementia. http://www.uptodate.com/home/index.html. Accessed June 28, 2010.
  5. Toro P, et al. Type II diabetes in mild cognitive impairment and Alzheimer's disease. Journal of Alzheimer's Disease. 2009;16:687.
  6. Cukierman-Yaffe T, et al. Relationship between baseline glycemic control and cognitive function in individuals with type 2 diabetes and other cardiovascular risk factors. Diabetes Care. 2009;32:221.
  7. Araki A, et al. Diabetes mellitus and geriatric syndromes. Geriatrics and Gerontology International. 2009;9:105.
  8. Middleton LE, et al. Promising strategies for prevention of dementia. Archives of Neurology. 2009;66:1210.
  9. Rockwood K, et al. The inclusion of cognition in vascular risk factor clinical practice guidelines. Clinical Interventions in Aging. 2009;4:425.
  10. Diabetes Prevention Program. National Institute of Diabetes and Digestive and Kidney Diseases. 2008. http://diabetes.niddk.nih.gov/dm/pubs/preventionprogram. Accessed July16, 2010.
  11. Preventing Alzheimer's disease and cognitive decline. National Institutes of Health State-of-the-Science Conference Statement. April 26-28, 2010. http://consensus.nih.gov/2010/docs/alz/ALZ_Final_Statement.pdf. Accessed June 25, 2010.
  12. Diabetes overview. National Institute of Diabetes and Digestive and Kidney Diseases. http://diabetes.niddk.nih.gov/dm/pubs/overview/index.htm. Accessed Aug. 6, 2010.
  13. 4 Steps to control your diabetes. For life. National Institutes of Health. http://www.ndep.nih.gov/media/4_Steps.pdf. Accessed Aug. 6, 2010.
AZ00050 Sept. 16, 2010

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