DefinitionBy Mayo Clinic staff
Diabetes insipidus (die-uh-BEE-teze in-SIP-uh-dus) is an uncommon disorder characterized by intense thirst, despite the drinking of fluids (polydipsia), and the excretion of large amounts of urine (polyuria). In most cases, it's the result of your body not properly producing, storing or releasing a key hormone, but diabetes insipidus can also occur when your kidneys are unable to respond properly to that hormone. Rarely, diabetes insipidus can occur during pregnancy (gestational diabetes insipidus).
You may assume diabetes insipidus and diabetes mellitus — the more common form of diabetes involving blood sugar — are related. Although the disorders share a name and have some common signs, diabetes mellitus (type 1 and type 2) and diabetes insipidus are unrelated.
Treatments are available to relieve your thirst and normalize your urine output.
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