Diabetes insipidus

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Symptoms

By Mayo Clinic staff

The most common signs and symptoms of diabetes insipidus are:

  • Extreme thirst
  • Excretion of an excessive amount of diluted urine

Depending on the severity of the condition, urine output can range from 2.6 quarts (about 2.5 liters) a day if you have mild diabetes insipidus to 16 quarts (about 15 liters) a day if the condition is severe and if you're taking in a lot of fluids. In comparison, the average urine output for a healthy adult is in the range of 1.6 to 2.6 quarts (about 1.5 to 2.5 liters) a day.

Other signs may include needing to get up at night to urinate (nocturia) and bed-wetting.

Infants and young children who have diabetes insipidus may have the following signs and symptoms:

  • Unexplained fussiness or inconsolable crying
  • Unusually wet diapers
  • Fever, vomiting or diarrhea
  • Dry skin with cool extremities
  • Delayed growth
  • Weight loss

When to see a doctor
See your doctor immediately if you notice the two most common signs of diabetes insipidus: excessive urination and extreme thirst.

References
  1. What is diabetes insipidus? Diabetes Insipidus Foundation. http://www.diabetesinsipidus.org. Accessed June 18, 2010.
  2. Diabetes insipidus. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/insipidus. Accessed June 18, 2020.
  3. Bichet DG. Diagnosis of polyuria and diabetes insipidus. http://www.uptodate.com/home/index.html. Accessed June 15, 2010.
  4. Bichet DG. Treatment of nephrogenic diabetes insipidus. http://www.uptodate.com/home/index.html. Accessed June 15, 2010.
  5. Rose BD, et al. Treatment of central diabetes insipidus. http://www.uptodate.com/home/index.html. Accessed June 15, 2010.
DS00799 Sept. 2, 2010

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