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Symptoms

By Mayo Clinic staff

Diabetic hyperosmolar syndrome may take days or even weeks to develop. Pay attention to possible signs and symptoms, which include:

  • High blood sugar level
  • Excessive thirst
  • Dry mouth
  • Increased urination
  • Warm, dry skin with no sweating
  • Fever
  • Sleepiness
  • Confusion
  • Hallucinations
  • Vision loss
  • Weakness on one side of the body
  • Convulsions
  • Coma

When to see a doctor
Consult your doctor if your blood sugar is persistently higher than the target range your doctor has recommended, or if you experience any signs or symptoms of diabetic hyperosmolar syndrome, such as:

  • Excessive thirst
  • Increased urination
  • Warm skin without sweating

Seek emergency care if:

  • Your blood sugar level is 600 mg/dL (33 mmol/L) or higher
  • You experience confusion, vision changes or weakness on one side of the body
References
  1. Kitabchi AE, et al. Hyperglycemic crises in adult patients with diabetes (Consensus statement). Diabetes Care. 2009:32;1335.
  2. Masharani U. Diabetes mellitus and hypoglycemia. In: McPhee SJ, et al. Current Medical Diagnosis and Treatment. 49th ed. New York, N.Y.: McGraw-Hill Medical; 2010. http://www.accessmedicine.com/content.aspx?aID=15524. Accessed Jan. 26, 2010.
  3. Masharani U, et al. Pancreatic hormones and diabetes mellitus. In: Gardner DG, et al. Greenspan's Basic and Clinical Endocrinology. 8th ed. New York, N.Y.: McGraw-Hill Medical; 2007. http://www.accessmedicine.com/content.aspx?aID=2633151. Accessed Jan. 26, 2010.
  4. Hyperosmolar hyperglycemic nonketotic syndrome (HHNS). American Diabetes Association. http://www.diabetes.org/living-with-diabetes/complications/hyperosmolar-hyperglycemic.html. Accessed Jan. 29, 2010.
  5. Kitabchi AE, et al. Clinical features and diagnosis of diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults. http://www.uptodate.com/home/index.html. Accessed Jan. 18, 2010.
  6. Stoner, G. Hyperosmolar hyperglycemic state. American Family Physician. 2005;71:1723.
  7. Standards of medical care in diabetes, 2010. American Diabetes Association. Diabetes Care. 2010;33(suppl):11.
  8. Collazzo-Clavell ML (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 1, 2010.
  9. Rosenow E (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 31, 2010.
DS00664 March 23, 2010

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