Dilated cardiomyopathy

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Risk factors

By Mayo Clinic staff

Many factors can change and enlarge your heart's main pumping chamber (left ventricle). The risk factors for dilated cardiomyopathy include:

  • High blood pressure (hypertension)
  • Hardening and narrowing of arteries (atherosclerosis)
  • Heart valve problems
  • Damage to the heart muscle from a previous heart attack
  • Rapid heart rate (tachycardia)
  • Family history of dilated cardiomyopathy
  • Alcoholism
  • Certain chemotherapy drugs for treating cancer
  • Cocaine abuse
  • Viral or bacterial infections of the heart muscle
  • Metabolic disorders, such as thyroid disease or diabetes
  • Absorbing too much iron from the food you eat (hemachromatosis)
  • Nutritional deficiencies of essential vitamins and minerals
  • Inflammation of heart muscle from immune system disorders
  • Metals and other toxic compounds, such as lead, mercury and arsenic
  • Neuromuscular disorders, such as muscular dystrophy
  • Pregnancy
References
  1. Jeffries JL, et al. Dilated cardiomyopathy. The Lancet. 2010;375:752.
  2. Dilated cardiomyopathy. American Heart Association. http://www.heart.org/idc/groups/heart-public/@wcm/@hcm/documents/downloadable/ucm_312224.pdf. Accessed July 3, 2011.
  3. Cardiomyopathy. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/cm/cm_all.html. Accessed July 3, 2011.
  4. Mestroni L, et al. Dilated cardiomyopathies. In: Fuster V, et al. Hurst's The Heart. 13th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=7811432. Accessed July 3, 2011.
  5. Bashore TM, et al. Heart disease. In McPhee SJ, et al. Current Medical Diagnosis & Treatment 2011. 50th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=3671. Accessed July 3, 2011.
  6. Hunt SA, et al. 2009 Focused update incorporated into the ACC/AHA 2005 guidelines for the diagnosis and management of heart failure in adults: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Journal of the American College of Cardiology. 2009;53:e1.
  7. Grogan M (expert opinion). Mayo Clinic, Rochester, Minn. July 31, 2011.
DS01029 Sept. 16, 2011

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