Causes
By Mayo Clinic staffThe bacterium Corynebacterium diphtheriae causes diphtheria. Usually C. diphtheriae multiply on or near the surface of the mucous membranes of the throat. C. diphtheriae spreads via three routes:
- Airborne droplets. When an infected person's sneeze or cough releases a mist of contaminated droplets, people nearby may inhale C. diphtheriae. Diphtheria spreads efficiently this way, particularly in crowded conditions.
- Contaminated personal items. People occasionally catch diphtheria from handling an infected person's used tissues, drinking from the person's unwashed glass, or coming into similarly close contact with other items on which bacteria-laden secretions may be deposited.
- Contaminated household items. In rare cases, diphtheria spreads on shared household items, such as towels or toys.
You can also come in contact with diphtheria-causing bacteria by touching an infected wound.
People who have been infected by the diphtheria bacteria and who haven't been treated can infect nonimmunized people for up to six weeks — even if they don't show any symptoms.
- Diphtheria. World Health Organization. http://www.who.int/mediacentre/factsheets/fs089/en/. Accessed Feb. 9, 2011.
- Diphtheria. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec14/ch172/ch172c.html. Accessed Feb. 9, 2011.
- Daybell DK, et al. Epidemiology and clinical features of diphtheria. http://www.uptodate.com/home/index.html. Accessed Feb. 9, 2011.
- Overturf GD. Corynebacterium diphtheriae. In: Long SS. Principles and Practice of Pediatric Infectious Diseases Revised Reprint. 3rd ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2009. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7020-3468-8..50002-X&isbn=978-0-7020-3468-8&uniqId=235245982-7. Accessed Feb. 10, 2011.
- Daybell DK, et al. Diagnosis and treatment of diphtheria. http://www.uptodate.com/home/index.html. Accessed Feb. 9, 2011.
- Recommended immunization schedule for adults aged 19 years and older — United States, 2013. Centers for Disease Control and Prevention http://www.cdc.gov/vaccines/schedules/hcp/child-adolescent.html. Accessed Feb. 19, 2013.
- Tetanus, diphtheria (Td) or tetanus, diphtheria, pertussis (Tdap) vaccine: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-td-tdap.pdf. Accessed Feb. 10, 2011.
- Bishai WR, et al. Diphtheria and other infections caused by corynebacteria and related species. In: Fauci AS, et al. Harrison's Online. 17th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aid=2898307. Accessed Feb. 10, 2011.
- Recommended immunization schedule for persons aged 0 through 18 years — United States, 2013. Centers for Disease Control and Prevention http://www.cdc.gov/vaccines/schedules/hcp/child-adolescent.html. Accessed Feb. 19, 2013.


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