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Risk factors

By Mayo Clinic staff

People who are at increased risk of contracting diphtheria include:

  • Children and adults who don't have up-to-date immunizations
  • People living in crowded or unsanitary conditions
  • People who have a compromised immune system
  • Anyone who travels to an area where diphtheria is endemic

Diphtheria rarely occurs in the United States and Europe, where health officials have been immunizing children against the condition for decades. However, diphtheria is still common in developing countries where immunization rates are low.

In areas where diphtheria is a standard vaccination, the disease is mainly a threat to unvaccinated or inadequately vaccinated people who travel internationally or have contact with people from less-developed countries.

References
  1. Diphtheria. World Health Organization. http://www.who.int/mediacentre/factsheets/fs089/en/. Accessed Feb. 9, 2011.
  2. Diphtheria. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec14/ch172/ch172c.html. Accessed Feb. 9, 2011.
  3. Daybell DK, et al. Epidemiology and clinical features of diphtheria. http://www.uptodate.com/home/index.html. Accessed Feb. 9, 2011.
  4. Overturf GD. Corynebacterium diphtheriae. In: Long SS. Principles and Practice of Pediatric Infectious Diseases Revised Reprint. 3rd ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2009. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7020-3468-8..50002-X&isbn=978-0-7020-3468-8&uniqId=235245982-7. Accessed Feb. 10, 2011.
  5. Daybell DK, et al. Diagnosis and treatment of diphtheria. http://www.uptodate.com/home/index.html. Accessed Feb. 9, 2011.
  6. Recommended immunization schedule for persons aged 0 through 6 years - United States 2011. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/recs/schedules/downloads/child/0-6yrs-schedule-pr.pdf. Accessed Feb. 10, 2011.
  7. Tetanus, diphtheria (Td) or tetanus, diphtheria, pertussis (Tdap) vaccine: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-td-tdap.pdf. Accessed Feb. 10, 2011.
  8. Bishai WR, et al. Diphtheria and other infections caused by corynebacteria and related species. In: Fauci AS, et al. Harrison's Online. 17th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aid=2898307. Accessed Feb. 10, 2011.
DS00495 March 12, 2011

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