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Tests and diagnosis
By Mayo Clinic staffDoctors may suspect diphtheria in a sick child who has a sore throat with a gray membrane covering the tonsils and throat. Doctors confirm the diagnosis by taking a sample of the membrane from the child's throat with a swab and having the sample grown (cultured) in a laboratory. Your doctor should notify the laboratory that diphtheria is suspected.
Doctors can also take a sample of tissue from an infected wound and have it tested in a laboratory, to check for the type of diphtheria that affects the skin (cutaneous diphtheria).
If a doctor suspects diphtheria, treatment begins immediately, even before the results of bacterial tests are available.
- Diphtheria. World Health Organization. http://www.who.int/mediacentre/factsheets/fs089/en/. Accessed Feb. 12, 2009.
- Diphtheria. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec14/ch172/ch172c.html. Accessed Feb. 12, 2009.
- Pegram PS. Epidemiology and clinical features of diphtheria. http://www.uptodate.com/home/index.html. Accessed Feb. 12, 2009.
- Bortolussi R, et al. Aerobic gram-positive bacilli. In: Cohen J, et al. Cohen & Powderly: Infectious Diseases. 2nd ed. St. Louis, Mo.: Mosby; 2004:2153.
- Daybell DK. Diagnosis and treatment of diphtheria. http://www.uptodate.com/home/index.html. Accessed Feb. 12, 2009.
- Recommended immunization schedule for persons aged 0 through 6 years. U.S. Department of Health and Human Services. http://www.cdc.gov/vaccines/recs/schedules/downloads/child/2009/09_0-6yrs_schedule_pr.pdf. Accessed Feb. 12, 2009.
- Vaccines and preventable diseases: Diphtheria vaccination. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/vpd-vac/diphtheria/default.htm. Accessed Feb. 12, 2009.
