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Prevention

By Mayo Clinic staff

If you have a history of a possible drug allergy, a skin test may help find out for certain. Tests for penicillin allergy are generally more reliable than are skin tests for allergies to other drugs.

Once you know you have a drug allergy, you'll need to avoid that drug and related drugs. Tell all of your health care providers, including your dentist, about your drug allergy. In case you're in an accident, you may want to wear a medical alert ID bracelet so that emergency workers will know about your allergy. In addition, you may want to carry a portable epinephrine injection (EpiPen, EpiPen Jr, Twinject) with you.

References
  1. Celik J. Drug allergy. In: Adkinson NF. Middleton's Allergy: Principles and Practice. 7th ed. Philadelphia, Pa.: Mosby Elsevier; 2008. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-323-05659-5..00068-1&isbn=978-0-323-05659-5&uniqId=281389325-3#4-u1.0-B978-0-323-05659-5..00068-1. Accessed Sept. 12, 2011.
  2. Medications and drug allergic reactions: Tips to remember.  American Academy of Allergy, Asthma & Immunology. http://www.aaaai.org/conditions-and-treatments/library/at-a-glance/medications-and-drug-allergic-reactions.aspx. Accessed Sept. 12, 2011.
  3. Drug hypersensitivity. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/immunology_allergic_disorders/allergic_and_other_hypersensitivity_disorders/drug_hypersensitivity.html#v996144. Accessed Sept. 12, 2011.
  4. Pichler WJ, et al. Drug hypersensitivity reactions: Pathomechanism and clinical symptoms. Medical Clinics of North America. 2010;94:645.
  5. Granowitz EV, et al. Antibiotic adverse reactions and drug interactions. Critical Care Clinics. 2008;24:421.
  6. Possible side-effects from vaccines. Centers for Disease Control and Prevention. http://www.cdc.gov/VACCINES/vac-gen/side-effects.htm. Accessed Sept. 12, 2011.
  7. Scherer K, et al. Danger signs in drug hypersensitivity. Medical Clinics of North America. 2010;94:681.
  8. Romano A, et al. Recent advances in the diagnosis of drug allergy. Current Opinion in Allergy and Clinical Immunolgy. 2007;7:299.
  9. Aberer W, et al. Provocation tests in drug hypersensitivity. Immunology and Allergy Clinics of North America. 2009;29:567.
DS01148 Oct. 14, 2011

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