Acetaminophen, Sodium Bicarbonate, and Citric Acid (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although the following side effects occur very rarely when 1 or 2 doses of this combination medicine is taken occasionally, they may be more likely to occur if: too much medicine is taken, the medicine is taken several times a day, or the medicine is taken for more than a few days in a row.

Check with your doctor immediately if any of the following side effects occur:

• Yellow eyes or skin

• Diarrhea
• Increased sweating
• Loss of appetite
• Nausea or vomiting
• Stomach cramps or pain
• Swelling, pain, or tenderness in the upper abdomen or stomach area

Check with your doctor as soon as possible if any of the following side effects occur:

• Bloody or black, tarry stools
• Bloody or cloudy urine, frequent urge to urinate, or sudden decrease in amount of urine
• Fever with or without chills (not present before treatment and not caused by the condition being treated)
• Headache (continuing)
• Increased blood pressure
• Mood or mental changes
• Muscle pain or twitching
• Nervousness or restlessness
• Pain (severe and/or sharp) in lower back and/or side
• Skin rash, hives, or itching
• Slow breathing
• Sores, ulcers, or white spots on lips or in mouth
• Sore throat (not present before treatment and not caused by the condition being treated)
• Swelling of face, fingers, ankles, feet, or lower legs
• Unpleasant taste
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Increased thirst

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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