Adefovir (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Dark urine
• General tiredness and weakness
• Light-colored stools
• Nausea and vomiting
• Upper right abdomen or stomach pain
• Yellow eyes and skin

• Blood in the urine
• Change in frequency of urination or amount of urine
• Difficult breathing
• Drowsiness
• Increased thirst
• Loss of appetite
• Swelling of the feet or lower legs
• Weakness

• Fast, shallow breathing
• General feeling of discomfort
• Muscle pain or cramping
• Shortness of breath
• Sleepiness
• Unusual tiredness or weakness

• Bloating
• Bone fractures, especially of the thigh bone
• Bone pain
• Chills
• Cloudy urine
• Constipation
• Convulsions
• Darkened urine
• Decreased frequency or amount of urine
• Fast heartbeat
• Fever
• Increase in the amount of urine
• Increased blood pressure
• Indigestion
• Lower back or side pain
• Muscular pain, tenderness, wasting, or weakness
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Swelling of the face, fingers, or lower legs
• Troubled breathing
• Weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach pain
• Headache
• Lack or loss of strength

• Acid or sour stomach
• Belching
• Bloated or full feeling
• Diarrhea
• Excess air or gas in the stomach or intestines
• Heartburn
• Passing gas
• Stomach discomfort, upset, or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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