It is very important that your doctor check you closely to see if the medicine is working properly. Blood and urine tests, certain laboratory tests, and chest X-rays will be needed before receiving this medicine and to check for unwanted effects.
Capillary leak syndrome (CLS) may occur immediately after receiving this medicine. Your doctor will monitor your blood pressure and pulse rate frequently to avoid lowering of blood pressure (hypotension).
Tell your doctor or nurse right away if you have unusual drowsiness, dullness, sleepiness, tiredness, weakness, or feeling of sluggishness; or unusual or changes in mood or behavior, such as irritability, confusion, or depression after receiving the medicine. These could be signs of serious medical problems.
Aldesleukin can temporarily affect the white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:
- If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.
- Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your skin.
- Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.
- Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.
- Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.
- Avoid contact sports or other situations where bruising or injury could occur.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.