Amsacrine (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Accumulation of pus or swollen, red, tender area of infection around the rectum
• Black tarry stools
• Blood in urine or stools
• Cough or hoarseness
• Fever or chills
• Lower back or side pain
• Painful or difficult urination
• Pinpoint red spots on skin
• Sores, ulcers, or white spots on lips, tongue, or inside mouth
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Abdominal pain or tenderness
• Blurred vision
• Confusion
• Dark urine
• Diarrhea
• Dizziness, faintness, or light-headedness
• Fast, pounding, or irregular heartbeat or pulse
• Fever
• Itching
• Nausea
• Palpitations
• Convulsions (seizures)
• Vomiting or vomiting of blood or material that looks like coffee grounds
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Burning, crawling, numbness, prickling, “pins and needles”, or tingling feelings
• Headache

• Bleeding gums
• Difficulty swallowing
• Hives
• Loss of appetite
• Loss of strength or energy
• Muscle or bone pain
• Pain or redness at site of injection
• Rash
• Redness and swelling of gums

This medicine often causes a temporary loss of hair. After treatment with amsacrine has ended, normal hair growth should return.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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