Anakinra (Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Chest pain
• Cough
• Diarrhea
• Fever or chills
• General feeling of discomfort or illness
• Headache
• Itching, pain, redness, swelling, tenderness or warmth on skin
• Joint pain
• Loss of appetite
• Muscle aches and pains
• Nausea
• Pain or tenderness around eyes and cheekbones
• Redness, bruising pain at the injection site
• Runny nose
• Shivering
• Shortness of breath
• Sneezing
• Sore throat
• Sweating
• Tightness in chest
• Trouble sleeping
• Unusual tiredness or weakness
• Vomiting
• Wheezing

• Black, sticky stools
• Difficulty in swallowing
• Itching
• Lower back pain or side pain
• Painful or difficult urination
• Pale skin
• Rash; hives; swelling of face or lips
• Ulcers, sores or white spots in mouth
• Unusual bruising or bleeding

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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