Anastrozole (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Blurred vision
• Chest pain or discomfort
• Dizziness
• Headache
• Nervousness
• Pounding in the ears
• Shortness of breath
• Slow or fast heartbeat
• Swelling of the feet or lower legs

• Arm, back, or jaw pain
• Chest tightness or heaviness
• Cough or hoarseness
• Difficult or painful urination
• Dizziness, severe
• Fever or chills
• Headache, continuing
• Increased blood pressure
• Lower back or side pain
• Nausea
• Pain, tenderness, bluish color, or swelling of the foot or leg
• Sore throat
• Sudden shortness of breath
• Sweating
• Unusual tiredness or weakness
• Vaginal bleeding (unexpected and heavy)

• Blistering, peeling, or loosening of the skin
• Hives
• Itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Red skin lesions, often with a purple center
• Sores, ulcers, or white spots in the mouth or on the lips
• Welts

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Back pain
• Belching
• Body aches or pain
• Bone pain
• Congestion
• Constipation
• Decrease in height
• Diarrhea
• Dry mouth
• Dryness or soreness of the throat
• Feeling of warmth
• Fever
• Flushing or redness of the skin, especially on the face and neck
• Heartburn
• Hot flashes
• Increased appetite
• Indigestion
• Lack or loss of strength
• Loss of appetite
• Mood or mental changes
• Pain in the back, ribs, arms, or legs
• Pain, general
• Pelvic pain
• Runny nose
• Skin rash
• Stomach discomfort, upset, or pain
• Tender, swollen glands in the neck
• Trouble in swallowing
• Voice changes
• Vomiting
• Weakness
• Weight loss

• Anxiety and confusion
• Breast pain
• Chills
• Cough producing mucus
• Difficulty breathing
• Dryness of the vagina
• General feeling of discomfort or illness
• Itching of the skin
• Joint pain and stiffness
• Loss of hair
• Muscle pain
• Numbness or tingling of the hands or feet
• Shivering
• Sleepiness or unusual drowsiness
• Trouble sleeping or sleeplessness
• Weight gain
• Wheezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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