Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
For 0.5% apraclonidineMore common- Allergic reaction (redness, itching, tearing of eye)
- Blurred vision or change in vision
- Chest pain
- Clumsiness or unsteadiness
- Depression
- Dizziness
- Eye discharge, irritation, or pain
- Irregular heartbeat
- Numbness or tingling in fingers or toes
- Raising of upper eyelid
- Rash around eyes
- Redness of eyelid, or inner lining of eyelid
- Swelling of eye, eyelid, or inner lining of eyelid
- Swelling of face, hands, or feet
- Wheezing or troubled breathing
- Allergic reaction (redness of eye or inner lining of eyelid, swelling of eyelid, watering of eye)
- Irregular heartbeat
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
For 0.5% apraclonidineMore common- Dryness of mouth
- Eye discomfort
- Change in taste or smell
- Constipation
- Crusting or scales on eyelid or corner of eye
- Discoloration of white part of eye
- Drowsiness or sleepiness
- Dry nose or eyes
- General feeling of discomfort or illness
- Headache
- Increased sensitivity of eyes to light
- Muscle aches
- Nausea
- Nervousness
- Paleness of eye or inner lining of eyelid
- Runny nose
- Sore throat
- Tiredness or weakness
- Trouble in sleeping
- Increase in size of pupil of eye
- Paleness of eye or inner lining of eyelid
- Raising of upper eyelid
- Runny nose
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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