Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These may include certain types of cancer, such as leukemia or bladder cancer. Discuss these possible effects with your doctor.
Check with your doctor immediately if any of the following side effects occur:
More common- Black, tarry stools
- Bladder pain
- Bleeding gums
- Blood in urine or stools
- Cloudy urine
- Body aches or pain
- Burning or stinging of skin
- Chest pain
- Chills
- Congestion
- Cough
- Difficult breathing
- Difficulty swallowing
- Dizziness
- Ear congestion
- Fast heartbeat
- Fever
- Frequent urge to urinate
- Headache
- Hives
- Hoarseness
- Itching
- Loss of voice
- Lower back or side pain
- Muscle aches
- Nasal congestion
- Nausea
- Pain or tenderness around eyes and cheekbones
- Painful cold sores or blisters on lips, nose, eyes, or genitals
- Painful or difficult urination
- Pain, redness, swelling, tenderness, warmth on skin
- Pale skin
- Pinpoint red spots on skin
- Puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
- Rapid heartbeat
- Runny nose
- Shortness of breath
- Skin rash
- Sneezing
- Sore throat
- Sores, ulcers, or white spots on lips or in mouth
- Stuffy nose
- Swollen glands;
- Tender, swollen glands in neck
- Tightness in chest
- Troubled breathing with exertion
- Unusual bleeding or bruising
- Unusual tiredness or weakness
- Voice changes
- Vomiting
- Wheezing
- Change in consciousness
- Convulsions
- Decreased urine
- Drowsiness
- Dry mouth
- Increased blood creatinine
- Increased blood pressure
- Increased thirst
- Irregular heartbeat
- Loss of appetite
- Mood changes
- Muscle pain or cramps
- Numbness or tingling in hands, feet, or lips
- Loss of consciousness
Get emergency help immediately if any of the following symptoms of overdose occur:
- Diarrhea
- Nausea
- Vomiting
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More Common- Acid or sour stomach
- Appetite decreased
- Belching
- Bleeding after defecation
- Bloody nose
- Blurred vision
- Bruise
- Bumps on skin
- Burning, crawling, itching, numbness, prickling, "pins and needles"; or tingling feelings
- Burning while urinating
- Confusion
- Diarrhea
- Difficulty having a bowel movement (stool)
- Difficulty in moving
- Discouragement
- Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
- Dry skin
- Fainting
- Fear
- Feeling of discomfort or illness;
- Feeling of sluggishness
- Feeling sad or empty
- Feeling unusually cold
- Flushing
- Full or bloated feeling or pressure in the stomach
- Heartburn
- Heart murmur
- Indigestion
- Inflamed tissue from infection at the site of injection
- Injection site bruising
- Irritability
- Itching at injection site
- Joint pain
- Lack of appetite
- Large, flat, blue or purplish patches in the skin
- Loss of interest or pleasure
- Mouth hemorrhage
- Muscle stiffness
- Nervousness
- Night sweats
- Pain in joints
- Postnasal drip
- Post procedural hemorrhage
- Redness of skin
- Shivering
- Sleeplessness
- Small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope
- Small lumps under the skin
- Small red or purple spots in mouth
- Soreness or discomfort to touch or pressure on stomach
- Stomach discomfort upset or pain
- Sweating
- Swelling of abdominal or stomach area
- Swelling of hands, ankles, feet, or lower legs
- Swelling or inflammation of the mouth
- Swelling with pits or depressions visible on skin
- Swollen joints
- Tongue ulceration
- Trouble concentrating
- Trouble sleeping
- Uncomfortable swelling around anus
- Unusual drowsiness
- Unusually warm skin
- Upper abdominal pain
- Weight loss
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


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