In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Children are especially sensitive to the effects of chloroquine. This may increase the chance of side effects during treatment. Overdose is especially dangerous in children. Taking as little as 1 tablet (300-mg strength) has resulted in the death of a small child. Children should avoid traveling to areas where there is a chance of getting malaria, unless they can take antimalarial medicines that are more effective than chloroquine.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of chloroquine in the elderly with use in other age groups.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Arsenic Trioxide
- Chloral Hydrate
- Perflutren Lipid Microsphere
- Rabies Vaccine
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Magnesium Carbonate
- Magnesium Hydroxide
- Magnesium Oxide
- Magnesium Trisilicate
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Blood disease (severe)—Chloroquine may cause blood disorders
- Eye or vision problems—Chloroquine, especially in high doses, may cause serious side effects affecting the eyes
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency—Chloroquine may cause serious side effects affecting the blood in patients with this deficiency
- Liver disease—May decrease the removal of chloroquine from the blood, increasing the chance of side effects
- Nerve or brain disease (severe), including convulsions (seizures)—Chloroquine may cause muscle weakness and, at high doses, seizures
- Porphyria—Chloroquine may cause episodes of porphyria to occur more frequently
- Psoriasis—Chloroquine may bring on severe attacks of psoriasis
- Stomach or intestinal disease (severe)—Chloroquine may cause stomach or intestinal irritation