Hydrocodone and Ibuprofen (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloody stools
• Burning feeling in the chest or stomach
• Congestion in the chest
• Changes in facial skin color
• Cough
• Diarrhea
• Difficulty with swallowing
• Fast or irregular breathing
• Fever
• Frequent urge to urinate
• Heartburn
• Inability to urinate
• Irregular heartbeat
• Lightheadedness or dizziness
• Loss of bladder control
• Puffiness or swelling of the eyelids or around the eyes
• Ringing or buzzing in the ears
• Shortness of breath, troubled breathing, tightness in the chest or wheezing
• Skin rash, hives, or itching
• Stomach pain
• Tenderness in the stomach

Get emergency help immediately if any of the following symptoms of overdose occur:

• Blurred vision
• Cold or clammy skin
• Confusion
• Difficulty hearing or ringing or buzzing in the ears
• Dizziness
• General feeling of illness
• Headache
• Mood or mental changes
• Nausea or vomiting
• Severe drowsiness
• Severe stomach pain
• Skin rash
• Slow heartbeat
• Slow or troubled breathing
• Stiff neck or back
• Swelling of the face, fingers, feet, or lower legs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Anxiety
• Constipation
• Dry mouth
• Gas
• Increased sweating
• Nervousness
• Pounding heartbeat
• Sleepiness
• Trouble in sleeping
• Unusual tiredness or weakness

• Decreased appetite
• Decrease in sexual ability
• Depression
• Headache
• Heartburn
• Increased thirst
• Irritability
• Mood or mental changes
• Mouth ulcers
• Pain or burning in the throat
• Runny nose
• Sensation of burning, warmth, heat, numbness, tightness, or tingling
• Slurred speech
• Stomach upset
• Thinking abnormalities
• Trembling or shaking of the hands or feet
• Unexplained weight loss
• Unusual feeling of well-being
• Visual disturbances

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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