Losartan and Hydrochlorothiazide (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Dry mouth
• Increased thirst
• Muscle cramps or pain
• Nausea or vomiting
• Unusual tiredness or weakness
• Weak or irregular heartbeat

• Black, tarry stools
• Blood in the urine or stools
• Cough or hoarseness accompanied by chills or fever, lower back or side pain, or painful or difficult urination
• Fainting
• Pinpoint red spots on the skin
• Pounding heartbeat
• Severe stomach pain, nausea, and vomiting
• Skin rash
• Swelling of the feet or lower legs
• Unusual bleeding or bruising

• Coma
• Confusion
• Convulsions
• Dark-colored urine
• Decreased urine output
• Fast or irregular heartbeat
• Fever
• Irritability
• Large, flat, blue, or purplish patches in the skin
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Light-colored stools
• Muscle spasms
• Muscle stiffness
• Muscle twitching
• Painful knees and ankles
• Raised red swellings on the skin, the buttocks, legs or ankles
• Restlessness
• Seizures
• Shortness of breath
• Swelling of the face, ankles, or hands
• Upper right abdominal or stomach pain
• Weakness
• Yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Cold or flu-like symptoms
• Dizziness
• Headache
• Increased sensitivity of the skin to sunlight
• Sore throat
• Stomach pain

• Dry cough
• Sinus problems

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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