In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of amlodipine and atorvastatin combination in the pediatric population. Safety and efficacy have not been established.
Appropriate studies have not been performed on the relationship of age to the effects of amlodipine to treat high blood pressure in children younger than 6 years of age. Safety and efficacy have not been established.
Atorvastatin alone is safe to use in boys and some girls 10 to 17 years of age for treating certain types of high cholesterol.
Teenage girls taking atorvastatin should be counseled on appropriate birth control methods to prevent pregnancy.
Appropriate studies have not been performed on the relationship of age to the effects of amlodipine and atorvastatin combination in the geriatric population. Safety and efficacy have not been established.
|All Trimesters||X||Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Fenofibric Acid
- Fusidic Acid
- St John's Wort
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Black Cohosh
- Interferon Beta
- Oat Bran
- St John's Wort
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
- Grapefruit Juice
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse, or history of or
- Liver disease, history of—Use with caution. May cause side effects to become worse.
- Convulsions (seizures), not well-controlled or
- Electrolyte or metabolic enzyme deficiencies or disorders or
- Hypotension (low blood pressure) or
- Infection, severe or
- Kidney disease, severe or
- Major surgery or trauma, recent—Patients with these conditions may be at risk of developing muscle and kidney problems.
- Coronary artery disease, severe, obstructive—Use of this medicine may result in other heart problems.
- Diabetes or
- Thyroid problems—Use with caution. May make these conditions worse.
- Heart disease (e.g., aortic stenosis)—Use with caution. The blood pressure-lowering effects of this medicine may be increased.
- Liver disease, active or
- Liver enzymes, elevated—Should not be used in patients with these conditions.
- Stroke, recent or
- Transient ischemic attack (TIA), recent—Atorvastatin may increase chance of having hemorrhagic stroke (stroke caused by bleeding in the brain).