Ezetimibe and Simvastatin (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal or stomach fullness
• Bloating
• Chills
• Constipation
• Darkened urine
• Fast heartbeat
• Fever
• Hives
• Hoarseness
• Indigestion
• Itching
• Joint pain
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Loss of appetite
• Nausea
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Rash
• Redness of the skin
• Shortness of breath
• Stiffness
• Swelling of the eyelids, face, lips, hands, or feet
• Tightness in the chest
• Trouble breathing or swallowing
• Vomiting
• Wheezing
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Body aches or pain
• Cough
• Diarrhea
• Difficulty with breathing
• Difficulty with moving
• Ear congestion
• General feeling of discomfort or illness
• Headache
• Loss of voice
• Muscle aches and pains or cramping
• Muscle stiffness
• Nasal congestion
• Pain in the arms or legs
• Runny nose
• Shivering
• Sneezing
• Sore throat
• Sweating
• Swollen joints
• Trouble sleeping
• Unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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