Cisplatin (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Also, because of the way cancer medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Discuss these possible effects with your doctor.

Check with your doctor immediately if any of the following side effects occur:

• Black, tarry stools
• Blood in urine or stools
• Cough or hoarseness accompanied by fever or chills
• Dizziness or faintness (during or shortly after a dose)
• Fast heartbeat (during or shortly after a dose)
• Fever or chills
• Lower back or side pain accompanied by fever or chills
• Painful or difficult urination accompanied by fever or chills
• Pain or redness at place of injection
• Pinpoint red spots on skin
• Swelling of face (during or shortly after a dose)
• Unusual bleeding or bruising
• Wheezing (during or shortly after a dose)

Check with your doctor as soon as possible if any of the following side effects occur:

• Joint pain
• Loss of balance
• Ringing in ears
• Swelling of feet or lower legs
• Trouble in hearing
• Unusual tiredness or weakness

• Convulsions (seizures)
• Loss of reflexes
• Loss of taste
• Numbness or tingling in fingers or toes
• Trouble in walking

• Agitation or confusion
• Blurred vision
• Change in ability to see colors (especially blue or yellow)
• Muscle cramps
• Sores in mouth and on lips

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Nausea and vomiting (severe)

• Loss of appetite

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Black, tarry stools
• Blood in urine or stools
• Convulsions (seizures)
• Cough or hoarseness
• Decrease in urination
• Fever or chills
• Loss of balance
• Loss of reflexes
• Loss of taste
• Lower back or side pain
• Numbness or tingling in fingers or toes
• Painful or difficult urination
• Pinpoint red spots on skin
• Ringing in ears
• Swelling of feet or lower legs
• Trouble in hearing
• Trouble in walking
• Unusual bleeding or bruising

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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