Lopinavir and Ritonavir (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloating
• Blurred vision
• Chills
• Constipation
• Darkened urine
• Dry mouth
• Fast heartbeat
• Fever
• Flushed, dry skin
• Fruit-like breath odor
• Increased hunger
• Increased thirst
• Increased urination
• Indigestion
• Loss of appetite
• Loss of consciousness
• Nausea
• Pains in the stomach, side, or abdomen, possibly moving to the back
• Sweating
• Troubled breathing
• Unexplained weight loss
• Vomiting
• Yellow eyes or skin

• Blistering, peeling, or loosening of the skin
• Chest pain or discomfort
• Cough
• Diarrhea
• Itching
• Joint or muscle pain
• Lightheadedness, dizziness, or fainting
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Shortness of breath
• Slow or irregular heartbeat
• Sore throat
• Sores, ulcers, or white spots in the mouth or on the lips
• Unusual tiredness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abnormal stools
• Acid or sour stomach
• Belching
• Headache
• Heartburn
• Lack or loss of strength
• Pain
• Skin rash
• Stomach discomfort, upset, or pain
• Trouble with sleeping

• Redistribution of body fat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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