Diclofenac (Topical Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Application site reactions, including skin rash; pain, tingling, or burning sensation
• Flu-like syndrome (body ache, headache, fever, with or without chills)
• Itching skin

• Application site reactions, including swelling; increased skin sensitivity; itching, redness, or pain caused by reaction from exposure to sun
• Blood in the urine
• Cough
• Decrease in body movement
• Dry, itching, or burning eyes
• Eye pain
• Fever
• Headaches, including migraines
• High blood pressure
• Increased sensitivity of the eyes to light
• Infection
• Nasal congestion
• Pain or tenderness around the eyes and cheekbones
• Redness or swelling of the eyes
• Shortness of breath
• Skin rash other than at the application site
• Sore throat
• Tightness in the chest
• Troubled breathing
• Ulcers or sores on the skin, other than at the application site
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Burning skin
• Dry skin
• Red skin
• Scaly skin
• Thickened skin
• Tingling skin

• Acne
• Back pain
• Belching
• Bleeding skin
• Chest pain
• Diarrhea
• Heartburn
• Indigestion
• Joint pain
• Lack or loss of strength
• Loss or thinning of the hair
• Muscle pain
• Neck pain
• Runny nose
• Stomach upset or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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