Dihydroergotamine (Nasal Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Chest pain
• Cough, fever, sneezing, or sore throat
• Feeling of heaviness in chest
• Irregular heartbeat
• Itching of the skin
• Numbness and tingling of face, fingers, or toes
• Pain in arms, legs, or lower back
• Pain in back, chest or left arm
• Pale bluish-colored or cold hands or feet
• Shortness of breath or troubled breathing
• Weak or absent pulses in legs

• Confusion
• Convulsions (seizures)
• Delirium
• Dizziness
• Headaches
• Nausea and/or vomiting
• Numbness, tingling, and/or pain in the legs or arms
• Shortness of breath
• Stomach pain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Burning or tingling sensation, dryness, soreness, or pain in the nose
• Change in sense of taste
• Diarrhea
• Dizziness
• Dry mouth
• Fatigue
• Headache
• Increased sweating
• Nausea and or vomiting
• Muscle stiffness
• Runny and or stuffy nose
• Sudden sweatings and feelings of warmth
• Sensation of burning, warmth, or heat
• Sore throat
• Sleepiness
• Unexplained nose bleeds
• Unusual tiredness or weakness

• Anxiety
• Blurred vision
• Cold clammy skin
• Confusion
• Congestion in chest
• Cough
• Decreased appetite
• Depression
• Difficulty swallowing
• Dizziness or lightheadedness when getting up from a lying or sitting position
• Ear pain
• Eye pain
• Fever
• Heartburn
• Increased watering of eyes
• Increased watering of the mouth
• Increased yawning
• Muscle weakness
• Nervousness
• Pinpoint red spots on skin
• Pounding heartbeat
• Red or irritated eyes
• Ringing or buzzing in ears
• Skin rash
• Stomach pain
• Sudden fainting
• Swelling of face, fingers, feet, or lower legs
• Trembling or shaking of hands or feet
• Trouble in sleeping
• Unusual feeling of well being

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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