Doxepin (Topical Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Burning, crawling, or tingling sensation of the skin
• Swelling at the site of application
• Worsening of eczema and itching

• Fever

• Abdominal pain and swelling
• Blurring of vision
• Convulsions (seizures)
• Decreased awareness or responsiveness
• Difficulty in breathing
• Difficulty in passing urine
• Dizziness, fainting, or lightheadedness
• Drowsiness
• Enlarged pupils
• Excessive dryness of mouth
• Extremely high fever or body temperature
• Extremely low body temperature
• Fast heartbeat
• Increased or excessive unconscious or jerking movements
• Incurable constipation
• Irregular heartbeat
• Unconsciousness
• Vomiting
• Weak pulse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Burning and/or stinging at the site of application
• Changes in taste
• Dizziness
• Drowsiness
• Dryness and tightness of skin
• Dryness of mouth and/or lips
• Emotional changes
• Headache
• Thirst
• Unusual tiredness or weakness

• Anxiety
• Irritation, tingling, scaling, and cracking of skin
• Nausea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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