Entacapone (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Absence of or decrease in body movements
• Hyperactivity
• Increase in body movements
• Seeing, hearing, or feeling things that are not there
• Twitching
• Twisting
• Uncontrolled repetitive movements of tongue, lips, face, arms, or legs

• Fever or chills
• Cough or hoarseness
• Lower back or side pain
• Painful or difficult urination

• Confusion
• Muscle cramps
• Pain
• Shortness of breath
• Stiffness
• Weakness
• Unusual tiredness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal pain
• Constipation
• Diarrhea
• Dizziness
• Fatigue
• Nausea

• Acid or sour stomach
• Anxiety
• Belching
• Bruising
• Burning feeling in chest or stomach
• Heartburn
• Difficult or labored breathing
• Dry mouth
• Indigestion
• Insomnia
• Irritability
• Loss of strength or energy
• Muscle pain or weakness
• Nervousness
• Passing gas
• Sleepiness or unusual drowsiness
• Small, red spots on skin
• Stomach discomfort, upset or pain
• Sweating increased
• Restlessness
• Tenderness in stomach area
• Tightness in chest
• Tremor
• Shortness of breath
• Unusual or unpleasant (after) taste
• Unusual weak feeling
• Wheezing

This medicine may cause your urine to turn brownish orange. This effect is harmless and will go away after you stop taking the medicine.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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