Fluticasone Propionate (Nasal Route)

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Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing the use of nasal fluticasone in children up to 4 years of age with use in other age groups. Corticosteroids taken by mouth or injection have been shown to slow growth in children and cause reduced adrenal gland function. Before nasal fluticasone is given to a child, you and the child's doctor should talk about the good this medicine will do as well as the risks of using it.

Geriatric

Although there is no specific information comparing use of nasal corticosteroids in the elderly with use in other age groups, these medicines are not expected to cause different side effects or problems in older people than they do in younger adults.

Pregnancy

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Atazanavir
• Boceprevir
• Bupropion
• Clarithromycin
• Darunavir
• Indinavir
• Itraconazole
• Ketoconazole
• Nefazodone
• Nelfinavir
• Primidone
• Ritonavir
• Saquinavir
• Telaprevir
• Telithromycin
• Tipranavir

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Glaucoma—Rare cases of glaucoma have been reported following use of nasal corticosteroids, including nasal fluticasone

• Herpes simplex (virus) infection of the eye or
• Infections (viral, bacterial, parasitic, or fungal)—Nasal corticosteroids may cover up the signs of these infections

• Injury to the nose (recent) or
• Nose surgery (recent) or
• Sores in the nose—Nasal corticosteroids may prevent proper healing of these conditions

• Tuberculosis (active or history of)—Nasal corticosteroids may cover up the signs of this infection or cause it to start up again

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