Lutropin Alfa (Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• Bloating
• Diarrhea
• Stomach or pelvic discomfort, aching, or heaviness

• Congenital abnormalities
• Ectopic pregnancy
• Postpartum fever
• Premature labor
• Spontaneous abortion

• Adnexal torsion as a complication of ovarian enlargement
• Blood in the peritoneal cavity
• Changes in skin color
• Cold hands and feet
• Ovarian enlargement (mild to moderate)
• Pain, redness, or swelling in the arm or leg
• Troubled breathing

Get emergency help immediately if any of the following symptoms of overdose occur:

• Abdominal or stomach pain
• Bloating
• Multiple gestation
• Rapid weight gain
• Severe nausea
• Vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Bloated or full feeling
• Breast pain
• Excess air or gas in the stomach or intestines
• Headache
• Pain
• Passing gas
• Unusual tiredness or weakness

• Body aches or pain
• Chills
• Cough
• Cramps
• Difficulty having a bowel movement (stool)
• Difficulty with breathing
• Ear congestion
• Fever
• Heavy bleeding
• Loss of voice
• Nasal congestion
• Ovarian disorder
• Pain
• Runny nose
• Sneezing
• Sore throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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