Loxapine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Difficulty with speaking or swallowing
• Lip smacking or puckering
• Loss of balance control
• Mask-like face
• Puffing of the cheeks
• Rapid or fine, worm-like movements of the tongue
• Restlessness or desire to keep moving
• Shuffling walk
• Slowed movements
• Stiffness of the arms and legs
• Trembling and shaking of the fingers and hands
• Uncontrolled chewing movements
• Uncontrolled movements of the arms or legs

• Constipation (severe)
• Difficult urination
• Inability to move the eyes
• Muscle spasms, especially of the neck and back
• Skin rash
• Twisting movements of the body

• Convulsions (seizures)
• Difficult or fast breathing
• Fast heartbeat or irregular pulse
• Fever (high)
• High or low blood pressure
• Increased blinking or spasms of the eyelid
• Increased sweating
• Loss of bladder control
• Muscle stiffness (severe)
• Sore throat and fever
• Uncontrolled twisting movements of neck, trunk, arms, or legs
• Unusual bleeding or bruising
• Unusual facial expressions or body positions
• Unusual tiredness or weakness
• Unusually pale skin
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Dizziness (severe)
• Drowsiness (severe)
• Muscle trembling, jerking, stiffness, or uncontrolled movements (severe)
• Troubled breathing (severe)
• Unusual tiredness or weakness (severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Blurred vision
• Confusion
• Dizziness, lightheadedness, or fainting
• Drowsiness
• Dryness of the mouth

• Constipation (mild)
• Decreased sexual ability
• Enlargement of breasts (males and females)
• Headache
• Increased sensitivity of the skin to sun
• Missing menstrual periods
• Nausea or vomiting
• Trouble with sleeping
• Unusual secretion of milk
• Weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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