Mercaptopurine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
  • Abdominal or stomach pain or tenderness
  • Black, tarry stools
  • Blood in the urine or stools
  • Clay colored stools
  • Cough or hoarseness
  • Dark urine
  • Decreased appetite
  • Fever or chills
  • Headache
  • Itching
  • Loss of appetite
  • Lower back or side pain
  • Nausea and vomiting
  • Painful or difficult urination
  • Pinpoint red spots on the skin
  • Skin rash
  • Swelling of the feet or lower legs
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
  • Yellow eyes or skin
Less common
  • Bleeding gums
  • Chest pain
  • Joint pain
  • Pale skin
  • Shortness of breath
  • Sore throat
  • Sores, ulcers, or white spots on the lips or in the mouth
  • Swollen glands
  • Troubled breathing with exertion
Incidence not known
  • Abdominal or stomach cramping or burning
  • Constipation
  • Diarrhea
  • Heartburn
  • Indigestion
  • Joint pain, stiffness, or swelling
  • Lower back or side pain
  • Vomiting of blood or material that looks like coffee grounds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Darkening of the skin
  • Headache
  • Weakness
Incidence not known
  • Hair loss or thinning of the hair
  • Low sperm count

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions
DR600895 Portions of this document last updated: Nov. 1, 2011

Source: Drug Information provided by: Micromedex

Copyright © 2012 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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