Mesalamine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal or stomach pain (severe)
• Bloody diarrhea
• Rectal bleeding

• Abdominal or stomach cramps (severe)
• Blurred vision
• Dizziness
• Fever
• Full or bloated feeling
• Headache (severe)
• Nervousness
• Pounding in the ears
• Pressure in the stomach
• Skin rash and itching
• Slow or fast heartbeat
• Swelling of the abdominal or stomach area
• Unusual tiredness or weakness

• Anxiety
• Back pain (severe)
• Blue or pale skin
• Chest pain, possibly moving to the left arm, neck, or shoulder
• Chills
• Nausea or vomiting
• Shortness of breath
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Confusion
• Deep or fast breathing with dizziness
• Diarrhea (severe or continuing)
• Difficult or labored breathing
• Dizziness or lightheadedness
• Drowsiness (severe)
• Feeling of constant movement of self or surroundings
• Headache (severe or continuing)
• Hearing loss or ringing or buzzing in the ears (continuing)
• Nausea or vomiting (continuing)
• Numbness of the feet, hands, and around the mouth
• Seizures
• Sensation of spinning
• Sweating
• Tightness in the chest
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach cramps or pain (mild)
• Diarrhea (mild)
• Headache (mild)
• Runny or stuffy nose
• Sneezing

• Acid or sour stomach
• Acne
• Back or joint pain
• Belching
• Difficulty with moving
• Excess air or gas in the stomach or intestines
• Hair loss or thinning of the hair
• Heartburn
• Indigestion
• Loss of appetite
• Muscle pain or stiffness
• Passing gas
• Stomach discomfort or upset

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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