Micafungin (Intravenous Route)
Original Article: http://www.mayoclinic.com/health/drug-information/DR600925
Micafungin (Intravenous Route)Drug Information provided by: Micromedex
US Brand Names
Micafungin is an antifungal medicine. It is used to help the body overcome serious fungus infections, such as candidemia, acute disseminated candidiasis, candida peritonitis and abscess, and esophageal candidiasis. Micafungin is also used to prevent candida infections in patients having a stem cell transplant .
This medicine is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of micafungin in the pediatric population. Safety and efficacy have not been established .
Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of micafungin in the elderly .
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Bleeding problems (e.g., hemolysis or hemolytic anemia) or
- Kidney problems—Use with caution. May make these conditions worse .
- Liver disease, moderate to severe—Higher blood levels of micafungin may result, increasing the chance of side effects.
A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins .
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects .
This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash; itching; swelling of the face, tongue, and throat; trouble breathing; or chest pain after you get the injection .
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:Less common
- Bone pain
- Chest pain
- Decreased urine
- Dry mouth
- Increased thirst
- Irregular heartbeat
- Lab results that show problems with liver
- Loss of appetite
- Lower back or side pain
- Mood or mental changes
- Muscle pain or cramps
- Muscle spasms or twitching
- Numbness or tingling in hands, feet, or lips
- Painful or difficult urination
- Shortness of breath
- Sore throat
- Sores, ulcers, or white spots on lips or in mouth
- Swollen glands
- Trouble breathing
- Ulcers, sores, or white spots in mouth
- Abdominal cramps
- Black, tarry stools
- Bleeding gums
- Blood in urine or stools
- Blurred vision
- Pale skin
- Pinpoint red spots on skin
- Pounding in the ears
- Slow or fast heartbeat
- Troubled breathing with exertion
- Unusual bleeding or bruising
- Unusual tiredness or weakness
- Cold, clammy skin
- Difficulty swallowing
- Fast, weak pulse
- Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- Skin rash
- Rash or redness
- Swelling of face, throat, or tongue
- Tightness in chest
- Back, leg, or stomach pains
- Bleeding gums
- Dark urine
- General body swelling
- Increased blood pressure
- Increased thirst
- Light-colored stools
- Muscle twitching
- Rapid weight gain
- Stomach pain
- Swelling of face, ankles, or hands
- Swelling of lower legs
- Troubled breathing
- Unpleasant breath odor
- Vomiting of blood
- White blood cell count decreased
- Yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common
- Bluish color
- Changes in skin color
- Feeling unusually cold; shivering
- Infusion site inflammation
- Stomach pain
- Swelling of foot or leg
- Acid or sour stomach
- Change in taste
- Confusion as to time, place, or person
- Difficulty having a bowel movement (stool)
- Feeling of warmth
- Holding false beliefs that cannot be changed by fact
- Injection site pain
- Loss of taste
- Redness of the face, neck, arms and occasionally upper chest
- Sleepiness or unusual drowsiness
- Stomach discomfort, upset, or pain
- Unusual excitement, nervousness, or restlessness
- Upper stomach pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.