When taken with certain drinks or other medicines, moclobemide and other monoamine oxidase inhibitors can cause very dangerous reactions, such as sudden high blood pressure (also called hypertensive crisis). To avoid such reactions, follow these rules of caution:
- Do not drink excessive amounts of alcohol.
- Do not take any other medicine unless approved or prescribed by your doctor. This especially includes nonprescription (over-the-counter [OTC]) medicine, such as medicine for colds (including nose drops or sprays), cough, hay fever, and appetite control; "stay awake" products; or products that make you sleepy.
Check with your doctor immediately if you experience any combination of the following symptoms: severe, throbbing headache that starts at the back of the head and radiates forward; stiff neck; fast or racing heartbeat; pounding, irregular, or slow heartbeat. These may be symptoms of a serious side effect that should have a doctor's attention.
Do not stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely.
Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position suddenly. Getting up slowly may help. When you get up from lying down, sit on the edge of the bed with your feet dangling for 1 or 2 minutes, then stand up slowly. If the problem continues or gets worse, check with your doctor.
This medicine may cause blurred vision or make some people drowsy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are unable to see well or are not alert.
Before having any kind of surgery, dental treatment, or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine or have used it within the past 2 weeks. Taking moclobemide together with medicines that are used during surgery, dental, or emergency treatments may increase the risk of serious side effects.
After you stop using this medicine, you must continue to exercise caution for at least 2 weeks with your foods, drinks, and other medicines, since these items may continue to react with moclobemide.