Natalizumab (Intravenous Route)

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Precautions

Your doctor will want to check your progress 3 months after the first injection, 6 months after the first injection, and every 6 months after that .

Tell your doctor if you are currently taking interferon beta (e.g., Avonex®, Betaseron®, Rebif®), azathioprine (e.g., Imuran®), 6-mercaptopurine (e.g., Purinethol®), cyclosporine (e.g., Gengraf®, Neoral®, Sandimmune®), or methotrexate (e.g., Rheumatrex®, Trexall®). Natalizumab should not be given together with these medicines .

This medicine may increase your risk of developing infections, including a serious brain infection called progressive multifocal leukoencephalopathy (PML). Check with your doctor right away if you are having more than one of these symptoms: back pain; blurred vision; confusion; convulsions; dizziness; drowsiness; fever; headache; or unusual tiredness or weakness .

Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: abdominal pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; itching; loss of appetite; nausea and vomiting; skin rash; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin .

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash; hives; itching; swelling of the face, tongue, and throat; trouble breathing; or chest pain after you get the injection .

Side Effects Proper Use

DR600975

Portions of this document last updated:

Nov. 1, 2009

Source: Drug Information provided by: Micromedex

Copyright © 2009 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.


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