If you will be taking this medicine for a long time, it is very important that your doctor check the progress of you or your child at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.
You should not take nelfinavir if you or your child are taking any of the following medicines. Using nelfinavir together with any of these medicines can cause very serious medical problems:
- Alfuzosin (Uroxatral®) or
- Amiodarone Cordarone®) or
- Ergot medicines (dihydroergotamine [DHE 45®], ergoloid mesylate [Hydergine®], ergonovine [Ergotrate®], ergotamine [Ergomar®], methylergonovine [Methergine®], methysergide [Sansert®]) or
- Esomeprazole (Nexium®) or
- Lansoprazole (Prevacid®) or
- Lovastatin (Advicor®, Altocor®, Mevacor®) or
- Midazolam (Versed®) or
- Omeprazole (Prilosec®) or
- Pantoprazole (Protonix®) or
- Pimozide (Orap®) or
- Quinidine (Quinaglute®) or
- Rabeprazole (Aciphex®) or
- Rifampin (Rifadin®) or
- Sildenafil (Revatio®) or
- Simvastatin (Simcor®, Vytorin®, Zocor®) or
- Triazolam (Halcion®).
Do not take other medicines unless they have been discussed with your doctor. This includes prescription and nonprescription (over-the-counter [OTC]) medicines, and herbal (e.g., St. John's wort) or vitamin supplements.
Tell your doctor if you are also taking sildenafil (Viagra®), tadalafil (Cialis®), or vardenafil (Levitra®). Taking these medicines together with nelfinavir may increase your risk of having side effects such as low blood pressure, changes in vision, or prolonged erection of the penis.
Birth control pills that contain estrogen may not work as well while you are using this medicine. To keep from getting pregnant, use another form of birth control together with your pills. Other forms include condoms, diaphragms, or contraceptive foams or jellies.
This medicine may increase blood sugar levels. Check with your doctor if you or your child notice a change in the results of your blood or urine sugar tests.
This medicine may cause you to have excess body fat. Tell your doctor if you or your child notice changes in your body shape, such as an increased amount of fat in the upper back and neck, or around the chest and stomach area. You might also lose fat from the legs, arms, and face.
When you start taking HIV medicines, your immune system may get stronger. If you or your child have certain infections, such as pneumonia or tuberculosis, you may notice new symptoms when your body tries to fight them. If this occurs, be sure to tell your doctor.
This medicine will not keep you from giving HIV to your partner during sex. Make sure you understand this and practice safe sex, even if your partner also has HIV, by using a latex condom or other barrier method. This medicine will not keep you from giving HIV to other people if they are exposed to your blood. Do not re-use or share needles with anyone.