Oprelvekin (Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

The side effects listed below include only those that might be caused by oprelvekin. To find out about other side effects that may be caused by the cancer medicines you are also receiving, see the information about those medicines.

Check with your doctor as soon as possible if any of the following side effects occur:

• Fast heartbeat
• Fluid retention
• Irregular heartbeat
• Shortness of breath
• Sore mouth or tongue
• Swelling of feet or lower legs
• White patches in mouth and/or on tongue

• Bloody eye
• Blurred vision
• Severe redness and peeling of skin

• Bleeding
• Blistering
• Bloody urine
• Blurred vision
• Burning
• Change in ability to see colors, especially blue or yellow
• Cloudy urine
• Coldness
• Cough
• Decrease or increase in amount of urine
• Difficulty swallowing
• Discoloration of skin
• Dizziness
• Fainting or lightheadedness
• Fast heartbeat
• Feeling of pressure
• Hives
• Increased blood pressure
• Increased thirst
• Infection
• Inflammation
• Itching
• Loss of appetite
• Lower back/side pain
• Lumps
• Nausea
• Numbness
• Pain
• Puffiness or swelling of the eyelids or around the eyes face, lips or tongue
• Rash
• Redness
• Scarring
• Shortness of breath
• Skin rash
• Soreness
• Stinging
• Stomach pain;
• Swelling
• Tenderness
• Tightness in chest
• Tingling
• Troubled breathing
• Ulceration
• Unusual tiredness or weakness
• Vomiting
• Warmth at site
• Weight gain
• Wheezing

This medicine may also cause the following side effect that your doctor will watch for:

• Heart rhythm problems

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Red eyes
• Weakness

• Numbness or tingling of hands or feet
• Skin discoloration
• Skin rash at place of injection

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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