Palifermin (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Fever

• Skin rash (severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Bad, unusual, or unpleasant (after) taste
• Blurred vision
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Change in taste
• Difficulty with moving
• Discoloration of the tongue
• Dizziness
• Flushing or redness of the skin
• Headache
• Increased sensitivity to pain
• Increased sensitivity to touch
• Itching skin
• Muscle pain or stiffness
• Nervousness
• Pain
• Pain in the joints
• Pounding in the ears
• Rash (mild)
• Slow or fast heartbeat
• Swelling
• Thickening of the tongue
• Tingling in the hands and feet
• Unusually warm skin

• Redness or swelling of the vagina
• Redness, swelling, or pain of the skin
• Scaling of the skin on the hands and feet
• Ulceration of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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