Pancrelipase (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
  • Skin rash or hives
With high doses
  • Bowel blockage
  • Diarrhea
  • Nausea
  • Stomach cramps or pain
With very high doses
  • Blood in the urine
  • Joint pain
  • Swelling of the feet or lower legs
With powder dosage form or powder from opened capsules
  • Shortness of breath
  • Stuffy nose
  • Tightness in the chest
  • Trouble breathing
With tablets
  • Irritation of the mouth
Incidence not known
  • Cough
  • Difficulty with swallowing
  • Dizziness
  • Fast heartbeat
  • Itching
  • Noisy breathing
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Redness of the skin
  • Severe stomach pain
  • Unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Blurred vision
  • Dry mouth
  • Flushed, dry skin
  • Fruit-like breath odor
  • Headache
  • Increased hunger
  • Increased thirst
  • Increased urination
  • Sweating
  • Unexplained weight loss
  • Vomiting
Less common
  • Abnormal feces
  • Anxiety
  • Bloated
  • Chills
  • Cold sweats
  • Coma
  • Confusion
  • Cool, pale skin
  • Depression
  • Excess air or gas in the stomach or intestines
  • Fever
  • Frequent bowel movements
  • Full feeling
  • Muscle aches
  • Nightmares
  • Passing gas
  • Runny nose
  • Seizures
  • Shakiness
  • Slurred speech
  • Sore throat
Incidence not known
  • Difficulty having a bowel movement (stool)
  • Difficulty moving
  • Muscle aching or cramping
  • Muscle pains or stiffness
  • Muscle spasm
  • Swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions
DR601061 Portions of this document last updated: Dec. 1, 2012

Source: Drug Information provided by: Micromedex

Copyright © 2013 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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