It is very important that your doctor check your progress at regular visits.
If your symptoms do not improve within 2 to 3 weeks, or if they become worse, check with your doctor.
If this medicine causes you to feel very tired or very weak or causes a loss of appetite, nausea, or vomiting, stop taking it and check with your doctor immediately. These may be early warning signs of more serious problems that could develop later.
Oral contraceptives (birth control pills) may not work properly if you take them while you are taking rifapentine. Unplanned pregnancies may occur. You should use a different means of birth control while you are taking rifapentine. If you have any questions about this, check with your health care professional.
Liver problems may be more likely to occur if you drink alcoholic beverages regularly while you are taking this medicine. Also, the regular use of alcohol may keep this medicine from working properly. Therefore, you should not drink alcoholic beverages while you are taking this medicine .
Rifapentine will cause the urine, stools, saliva, sputum, sweat, and tears to turn reddish-orange to reddish-brown. This is to be expected while you are taking this medicine. This effect may cause soft contact lenses to become permanently discolored. Standard cleaning solutions may not take out all the discoloration. Therefore, it is best not to wear soft contact lenses while taking this medicine. Hard contact lenses are not discolored by rifapentine. If you have any question about this, check with your doctor.
Rifapentine can lower the number of white blood cells in your blood temporarily, increasing the chance of getting infection. It can also lower the number of platelets, which are necessary for proper blood clotting. These problems may result in a greater chance of getting certain infections, slow healing, and bleeding of the gums. Be careful when using a regular toothbrush, dental floss, or a toothpick. Dental work should be delayed until your blood counts have returned to normal. Check with your medical doctor or dentist if you have any questions about proper oral hygiene (mouth care) during treatment.
Before you have any medical tests, tell the doctor in charge that you are taking this medicine.