Rifapentine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Blood in urine
• Joint pain
• Lower back or side pain
• Swelling of feet or lower legs

• Aggressive reaction
• Black, tarry stools
• Blood in stools
• Nausea
• Pinpoint red spots on skin
• Severe abdominal or stomach pain
• Sore throat and fever
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Yellow eyes or skin
• Vomiting

• Diarrhea
• Dizziness
• Severe or continuing headaches
• Increase in blood pressure

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acne
• Constipation
• Loss of appetite

This medicine commonly causes reddish-orange to reddish-brown discoloration of urine, stools, saliva, sputum, sweat, and tears. This side effect does not usually need medical attention.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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