Tenofovir (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Chest pain
• Cough
• Fever or chills
• Shortness of breath
• Sneezing
• Sore throat
• Tightness in the chest
• Troubled breathing
• Wheezing

• Abdominal or stomach discomfort
• Decreased appetite
• Diarrhea
• Fast, shallow breathing
• General feeling of discomfort
• Muscle pain or cramping
• Nausea
• Sleepiness
• Unusual tiredness or weakness

• Agitation
• Bloating
• Bloody or cloudy urine
• Bone pain
• Coma
• Confusion
• Constipation
• Convulsions or seizures
• Darkened urine
• Decreased frequency or amount of urine
• Depression
• Difficult or painful urination
• Dizziness
• Fast heartbeat
• Fever
• Headache
• Hostility
• Increased blood pressure
• Increased thirst
• Indigestion
• Irritability
• Lethargy
• Loss of appetite
• Muscle twitching
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Stupor
• Swelling of the face, fingers, or lower legs
• Vomiting
• Weight gain
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Back pain
• Hives or welts
• Itching skin
• Lack or loss of strength
• Pain
• Redness of the skin
• Skin rash

• Acid or sour stomach
• Belching
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Difficulty with moving
• Heartburn
• Joint pain
• Muscle pains or stiffness
• Passing of gas
• Redistribution or accumulation of body fat
• Sleeplessness
• Stomach pain or upset
• Swollen joints
• Trouble with sleeping
• Unable to sleep
• Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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