It is important that your doctor check your progress at regular visits. Laboratory tests will have to be done every few months while you are taking this medicine to make sure that the gallstones are dissolving and your liver is working properly.
Do not take aluminum-containing antacids (e.g., ALternaGEL®, Maalox®), cholestyramine (Questran®), colestipol (Colestid®), clofibrate (Atromid-S®), or estrogen or birth control pills while taking ursodiol. To do so may keep ursodiol from working properly. Before using these medicines, check with your doctor first .
Check with your doctor immediately if severe abdominal or stomach pain, especially toward the upper right side, or severe nausea and vomiting occur. These symptoms may mean that you have other medical problems or that your gallstone condition needs your doctor's attention.